Development of in situ Bio-Sensor to Detect Antibodies using Ultrasonic Guided Wave Propagation

Faculty Mentor

Dr. Hossain Ahmed, Department of Mechanical Engineering, Assistant Professor, Corresponding

Location

Poster 119

Session Format

Poster Presentation

Academic Unit

Department of Civil Engineering

Background

  • Aims to develop a biosensor to detect antibodies using ultrasonic guided waves. Guided waves travel long distances with little loss in energy, making its products ideal due to low-cost and accuracy.

  • Antibodies are created by the immune system to fight off infections and are produced after infection or vaccination against an infection. They are structured proteins that only bind to its specific antigen using a lock-and-key mechanism which helps eliminate antigens from the human body by neutralization.

  • Previous studies focused on bio-sensing mechanisms to identify only one antibody or used only one cantilever beam as detection device. Whereas this project combines multiple beams and ultrasonic guided wave propagation to detect more than one antibody.

  • Guided waves are generated by two parallel plates separated by a certain distance. Using the piezoelectric phenomenon, guided waves can be generated in a thin plate. The piezoelectric phenomenon is an occurrence in certain solid materials in which electrical potential is generated in response to mechanical energy, and vice versa.

  • Piezoelectric material, also known as smart material, has multiple properties which make them ideal for use of sensors. Specifically, PZT-5H has very good permittivity, high strain constants, high strain output and high charge output.

Keywords

Allen E. Paulson College of Engineering and Computing Student Research Symposium, Situ Bio-Sensor

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.

Presentation Type and Release Option

Presentation (File Not Available for Download)

Start Date

2022 12:00 AM

January 2022

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Development of in situ Bio-Sensor to Detect Antibodies using Ultrasonic Guided Wave Propagation

Poster 119