Development of in situ Bio-Sensor to Detect Antibodies using Ultrasonic Guided Wave Propagation
Faculty Mentor
Dr. Hossain Ahmed, Department of Mechanical Engineering, Assistant Professor, Corresponding
Location
Poster 119
Session Format
Poster Presentation
Academic Unit
Department of Civil Engineering
Background
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Aims to develop a biosensor to detect antibodies using ultrasonic guided waves. Guided waves travel long distances with little loss in energy, making its products ideal due to low-cost and accuracy.
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Antibodies are created by the immune system to fight off infections and are produced after infection or vaccination against an infection. They are structured proteins that only bind to its specific antigen using a lock-and-key mechanism which helps eliminate antigens from the human body by neutralization.
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Previous studies focused on bio-sensing mechanisms to identify only one antibody or used only one cantilever beam as detection device. Whereas this project combines multiple beams and ultrasonic guided wave propagation to detect more than one antibody.
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Guided waves are generated by two parallel plates separated by a certain distance. Using the piezoelectric phenomenon, guided waves can be generated in a thin plate. The piezoelectric phenomenon is an occurrence in certain solid materials in which electrical potential is generated in response to mechanical energy, and vice versa.
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Piezoelectric material, also known as smart material, has multiple properties which make them ideal for use of sensors. Specifically, PZT-5H has very good permittivity, high strain constants, high strain output and high charge output.
Keywords
Allen E. Paulson College of Engineering and Computing Student Research Symposium, Situ Bio-Sensor
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Presentation Type and Release Option
Presentation (File Not Available for Download)
Start Date
2022 12:00 AM
January 2022
Development of in situ Bio-Sensor to Detect Antibodies using Ultrasonic Guided Wave Propagation
Poster 119