Understanding the Role of Heparan Sulfate Proteoglycan (Hspg2) in Brain and Behavioral Development

Location

Russell Student Union, Statesboro Campus- Room 2048

Document Type and Release Option

Thesis Presentation (Restricted to Georgia Southern)

Faculty Mentor

Dr. Vinoth Sittaramane

Faculty Mentor Email

[email protected]

Presentation Year

2021

Start Date

17-11-2021 6:00 PM

End Date

17-11-2021 7:00 PM

Keywords

Georgia Southern University, Honors College, Honors Symposium, Presentation

Description

Heparan Sulfate Proteoglycan 2 (Hspg2) is a highly conserved gene that expresses Perlecan, an extracellular matrix protein implicated in the development of the heart, bones, and muscles. Hspg2 is expressed in the developing zebrafish brain especially in the retinal ganglions, midbrain, and hindbrain regions. The locations and cellular phenotypic defects of these brain blood vessels are yet to be described. In order to determine these factors, staining, imaging, and analyzing the blood vessels and blood cells in zebrafish larval brains must be conducted.

Academic Unit

College of Science and Mathematics

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Nov 17th, 6:00 PM Nov 17th, 7:00 PM

Understanding the Role of Heparan Sulfate Proteoglycan (Hspg2) in Brain and Behavioral Development

Russell Student Union, Statesboro Campus- Room 2048

Heparan Sulfate Proteoglycan 2 (Hspg2) is a highly conserved gene that expresses Perlecan, an extracellular matrix protein implicated in the development of the heart, bones, and muscles. Hspg2 is expressed in the developing zebrafish brain especially in the retinal ganglions, midbrain, and hindbrain regions. The locations and cellular phenotypic defects of these brain blood vessels are yet to be described. In order to determine these factors, staining, imaging, and analyzing the blood vessels and blood cells in zebrafish larval brains must be conducted.