Microwave Assisted-Knoevenagel Condensation and Photodimerization of trans-2-Chlorocinnamic Acid
Primary Faculty Mentor’s Name
Koushik Banerjee
Proposal Track
Student
Session Format
Poster
Abstract
Originally modified from the aldol reaction, Knoevenagel condensation is an organic reaction that is widely used for the formation of carbon-carbon bonds. Past studies have shown that cinnamic acid derivatives naturally occur in the plants that humans consume. Due to their biological activities, such as antioxidants, antidiabetic, and anticancer properties, they aid in the production of various pharmaceutical ingredients. In the synthesis of trans-2-chlorocinnamic acid from microwave assisted Knoevenagel condensation reaction, 70.8% of product was recovered and a cyclobutane derivative was produced via a solid-state photodimerization reaction. Based on the analysis of the 1H-NMR results, there was greater than a 99% conversion from trans-2-chlorocinnamic to the photodimerization cyclobutane derivative.
Keywords
Knoevenagel condensation, trans-2-chlorocinnamic, photodimerization, cyclobutane derivative, cinnamic acid derivatives
Award Consideration
1
Location
Concourse and Atrium
Presentation Year
2015
Start Date
11-7-2015 2:10 PM
End Date
11-7-2015 3:20 PM
Publication Type and Release Option
Presentation (Open Access)
Recommended Citation
Lor, Blia, "Microwave Assisted-Knoevenagel Condensation and Photodimerization of trans-2-Chlorocinnamic Acid" (2015). Georgia Undergraduate Research Conference (2014-2015). 41.
https://digitalcommons.georgiasouthern.edu/gurc/2015/2015/41
Microwave Assisted-Knoevenagel Condensation and Photodimerization of trans-2-Chlorocinnamic Acid
Concourse and Atrium
Originally modified from the aldol reaction, Knoevenagel condensation is an organic reaction that is widely used for the formation of carbon-carbon bonds. Past studies have shown that cinnamic acid derivatives naturally occur in the plants that humans consume. Due to their biological activities, such as antioxidants, antidiabetic, and anticancer properties, they aid in the production of various pharmaceutical ingredients. In the synthesis of trans-2-chlorocinnamic acid from microwave assisted Knoevenagel condensation reaction, 70.8% of product was recovered and a cyclobutane derivative was produced via a solid-state photodimerization reaction. Based on the analysis of the 1H-NMR results, there was greater than a 99% conversion from trans-2-chlorocinnamic to the photodimerization cyclobutane derivative.
