Biostatistics, Epidemiology & Environmental Health Sciences: Faculty Publications

Statistical Considerations for Clinical Trials During COVID-19: Confirmatory Adaptive Platform Trial (CAPT) Design for COVID-19 Treatment (Part II)

Document Type

Article

Publication Date

5-10-2020

Publication Title

LinkedIn

Abstract

Part II of the article that describes confirmatory adaptive platform trial (CAPT) design for COVID-19 treatment development. We describe the methodological foundation of adaptive designs. We provide statistical methods for CAPT design, covering topics on sequential randomizations, adaptive group sequential designs, and sample size adjustment.

Copyright

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