1, 2, 3 Triazoles α- Amino Acid Derivatives as Drug Candidates
Location
College of Science and Mathematics (COSM)
Session Format
Poster Presentation
Co-Presenters and Faculty Mentors or Advisors
Dr. Rebecca Kocerha, Faculty Advisor
Abstract
1, 2, 3 Triazoles appear to have anticancer, antibacterial, and antifungal properties. Given these behaviors, it is possible to utilize the biological activity of these triazole units and exploit amino acid transporters to obtain the uptake of the derivatives to ultimately use as anticancer drug candidates. After synthesizing novel 1, 2, 3 – triazole compounds, cell-based anticancer investigations can be conducted. The synthesized molecules will be used to assess cancer cell growth in dose-response studies. The practicality of the use of the molecules as anticancer drug candidates will be evaluated using a panel of cancer cell lines. This would be beneficial to society because cancer treatments are very limited. The possibility of a new treatment would be revolutionary, especially if it is less invasive than some of the traditional treatments.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Presentation Type and Release Option
Presentation (Open Access)
Recommended Citation
Blount, Grace, "1, 2, 3 Triazoles α- Amino Acid Derivatives as Drug Candidates" (2021). GS4 Georgia Southern Student Scholars Symposium. 61.
https://digitalcommons.georgiasouthern.edu/research_symposium/2021/2021/61
1, 2, 3 Triazoles α- Amino Acid Derivatives as Drug Candidates
College of Science and Mathematics (COSM)
1, 2, 3 Triazoles appear to have anticancer, antibacterial, and antifungal properties. Given these behaviors, it is possible to utilize the biological activity of these triazole units and exploit amino acid transporters to obtain the uptake of the derivatives to ultimately use as anticancer drug candidates. After synthesizing novel 1, 2, 3 – triazole compounds, cell-based anticancer investigations can be conducted. The synthesized molecules will be used to assess cancer cell growth in dose-response studies. The practicality of the use of the molecules as anticancer drug candidates will be evaluated using a panel of cancer cell lines. This would be beneficial to society because cancer treatments are very limited. The possibility of a new treatment would be revolutionary, especially if it is less invasive than some of the traditional treatments.
