Actigraphy-Derived Sleep Metrics are Related to Metabolic but Not Vascular Health Measures in Young Adults

Location

Waters College of Health Professions (WCHP)

Session Format

Poster Presentation

Co-Presenters and Faculty Mentors or Advisors

Dr. Gregory Grosicki, Faculty Advisor

Abstract

Insufficient sleep is an emerging risk factor for cardiometabolic disease.

PURPOSE: To assess relationships between actigraphy-derived sleep metrics and measures of cardiometabolic health in young adults.

METHODS: Forty-four individuals (23±5yrs; 20 females) participated in this study. Wrist-worn actigraphy was used to characterize 7-day conventional sleep metrics including sleep efficiency, total sleep time, wake after sleep onset, and number of awakenings, and z-scores for each of these variables were summed to generate a composite sleep score (higher score=better sleep). Sleep regularity (SR), the standard deviation of sleep duration, was quantified as a novel index of sleep habits. Vascular health measures including central pressures and augmentation index at a heart rate of 75 beats per minute were quantified via pulse wave analysis, and arterial stiffness was evaluated using carotid femoral pulse wave velocity. Fasting blood glucose (FBG) was measured with a fingerstick blood draw. Relationships among sleep score and SR with vascular and metabolic health were evaluated.

RESULTS: FBG (86.8±7.3mg/dL) was related to SR (r2=0.106; P0.05). Sleep score and SR were not related (P>0.05) to measures of vascular health.

CONCLUSION: Consistency of sleep duration may be important to consider for preserving metabolic health in young adults.

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Presentation (Open Access)

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Actigraphy-Derived Sleep Metrics are Related to Metabolic but Not Vascular Health Measures in Young Adults

Waters College of Health Professions (WCHP)

Insufficient sleep is an emerging risk factor for cardiometabolic disease.

PURPOSE: To assess relationships between actigraphy-derived sleep metrics and measures of cardiometabolic health in young adults.

METHODS: Forty-four individuals (23±5yrs; 20 females) participated in this study. Wrist-worn actigraphy was used to characterize 7-day conventional sleep metrics including sleep efficiency, total sleep time, wake after sleep onset, and number of awakenings, and z-scores for each of these variables were summed to generate a composite sleep score (higher score=better sleep). Sleep regularity (SR), the standard deviation of sleep duration, was quantified as a novel index of sleep habits. Vascular health measures including central pressures and augmentation index at a heart rate of 75 beats per minute were quantified via pulse wave analysis, and arterial stiffness was evaluated using carotid femoral pulse wave velocity. Fasting blood glucose (FBG) was measured with a fingerstick blood draw. Relationships among sleep score and SR with vascular and metabolic health were evaluated.

RESULTS: FBG (86.8±7.3mg/dL) was related to SR (r2=0.106; P0.05). Sleep score and SR were not related (P>0.05) to measures of vascular health.

CONCLUSION: Consistency of sleep duration may be important to consider for preserving metabolic health in young adults.