Selective Mating in a Continuous Model of Epistasis
Document Type
Article
Publication Date
12-1-2005
Publication Title
Applied Mathematics and Computation
DOI
10.1016/j.amc.2005.01.059
ISSN
0096-3003
Abstract
Epistasis is the interaction between two or more genes to control a single phenotype. We model epistasis with a two-locus two-allele problem. The resulting model allows us to examine both population sizes as well as genotypic and phenotypic frequencies. In the context of an example, we show that if epistasis results in an undesirable phenotype, such as a genetically transmitted disease or condition, elimination of undesirable phenotypes from the population through selective breeding may be possible, although such selective breeding could lead to an increase in less desirable phenotypes and possibly the elimination of desirable phenotypes.
Recommended Citation
Braselton, James P., Martha L. Abell, Lorraine Braselton.
2005.
"Selective Mating in a Continuous Model of Epistasis."
Applied Mathematics and Computation, 171 (1): 225-241.
doi: 10.1016/j.amc.2005.01.059
https://digitalcommons.georgiasouthern.edu/math-sci-facpubs/439
