Peptide Nucleic Acids Synthesis and Analysis
Location
Armstrong Campus, Solms Hall, Room 214, Session 1
Document Type and Release Option
Thesis Presentation (Open Access)
Faculty Mentor
Dr. Nathaniel Shank
Faculty Mentor Email
nshank@georgiasouthern.edu
Presentation Year
2022
Start Date
29-4-2022 12:50 PM
End Date
29-4-2022 1:50 PM
Description
Peptide nucleic acids (PNAs) are oligonucleotide analogues with the sugar-phosphate backbone replaced by the pseudopeptide skeleton, functioning as antigene/antisense chemical agents, initially designed by Nielson and coworkers. PNAs used the natural nucleobases to form hybridization by the Watson-Crick base pairing. This project focuses on the synthesis and optimization of 11mer PNA attracted to a protein.
Academic Unit
College of Science and Mathematics
Peptide Nucleic Acids Synthesis and Analysis
Armstrong Campus, Solms Hall, Room 214, Session 1
Peptide nucleic acids (PNAs) are oligonucleotide analogues with the sugar-phosphate backbone replaced by the pseudopeptide skeleton, functioning as antigene/antisense chemical agents, initially designed by Nielson and coworkers. PNAs used the natural nucleobases to form hybridization by the Watson-Crick base pairing. This project focuses on the synthesis and optimization of 11mer PNA attracted to a protein.
