Location

Thesis Presentation- College of Science and Mathematics

Document Type and Release Option

Thesis Presentation (Open Access)

Faculty Mentor

Dr. Abid Shaikh

Faculty Mentor Email

malnu@georgiasouthern.edu

Presentation Year

2020

Start Date

4-2020 12:00 AM

End Date

5-2020 12:00 AM

Keywords

Georgia Southern University, Honors Program, Thesis Presentation

Description

While studying in vivo toxicity of this molecule in zebrafish (Danio rerio) embryo, we observed that it has a unique biological activity that causes a sudden inactivity in embryo movement. Continued investigation revealed that this molecule blocks sodium channels in neurons causing a temporary anesthesia in Danio rerio embryo.

Academic Unit

College of Science and Mathematics

Comments

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Structure Activity Relationship (SAR) Studies of Neurotoxin Quinoline-Derivatives

Thesis Presentation- College of Science and Mathematics

While studying in vivo toxicity of this molecule in zebrafish (Danio rerio) embryo, we observed that it has a unique biological activity that causes a sudden inactivity in embryo movement. Continued investigation revealed that this molecule blocks sodium channels in neurons causing a temporary anesthesia in Danio rerio embryo.