Honors College Theses

Publication Date

10-31-2023

Major

Biology (B.A.)

Document Type and Release Option

Thesis (open access)

Faculty Mentor

Aaron Schrey

Abstract

Acute lymphocytic leukemia (ALL) is the most common type of childhood cancer. Leukemia is a type of cancer that involves the bone marrow and blood. This research study examined prominent genes in the disease. Two groups of genes, tumor suppressor and cell differentiation, were compared using statistical analysis to compare their binding potential and epigenetic potential. It is most likely that I failed to detect significant differences either because these genes’ function in the disease etiology is not strongly contexed to changes in expression, or that the magnitude of the differences were too slight to be detected with these methods. Childhood cancer is the number one cause of disease in children in the United States yet receives only 4% of funding per year. This lack of funding could potentially close the door on discovering new, safer treatments for children.

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