Honors College Theses

Publication Date

4-20-2015

Major

Chemistry (B.S.)

Document Type and Release Option

Thesis (restricted to Georgia Southern)

Faculty Mentor

John Stone

Abstract

Gold nanoparticle complexes continue to be utilized as novel therapeutic materials. While offering interesting optical and physical properties, long- term stability, and are non-cytotoxic, they also possess a large surface area making the conjugation of a large number of polyelectrolytes, antibodies, or proteins to the particle surface possible. In the current study, we are dual functionalizing gold nanorods with iron oxide and an antibody specific to the bacteria Pseudomonas aeruginosa. These gold nanorod composites can be manipulated under a magnetic field and the antibody can bind to the receptors on the bacterium. This medicinal gold nanorod composite is being investigated for its ability to target and subsequently remove the bacterium Pseudomonas aeruginosa from a solution-based environment.

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