Association Between Markers of Cardiacparasympathetic Function and Myocardial Oxygen Supply Demand Balance in Young Adults
Document Type
Article
Publication Date
2024
Publication Title
International Journal of Exercise Science: Conference Proceedings
Abstract
BACKGROUND: The subendocardial viability ratio (SEVR) is an index of myocardial oxygen supply relative to demand, with lower values suggestive of increased cardiovascular risk. We aimed to determine if indices of cardiac-parasympathetic function were associated with SEVR in young adults. METHODS: Thirty-eight healthy young men (n = 19, 24 ± 4 yrs, 27 ± 4 kg/m2) and women (n = 19, 22 ± 3 yrs, 26 ± 4 kg/m2) participated in the study. Heart rate variability (HRV) was used to index resting cardiac-parasympathetic function. Participants performed post-waking HRV recordings for 60 s in the supine and standing positions for seven consecutive days. The average root-mean square of successive differences (RMSSD) from each position was recorded for analysis. Relative (%) heart rate recovery at one min (HRR1) and two min (HRR2) post-graded maximal exercise test on a cycle ergometer were subsequently obtained to index post-exercise cardiac-parasympathetic reactivation. SEVR was measured in a fasted state via pulse wave analysis approximately 1 h before the graded exercise test. RESULTS: In men, standing LnRMSSD (3.46 ± 0.46, r = 0.52), HRR1 (13 ± 5%, r = 0.46) and HRR2 (19 ± 7%, r = 0.50) were associated (P <0.05) with SEVR (154 ± 32%). In women, only HRR2 (19 ± 8%, r = 0.52) was associated (P <0.05) with SEVR (126 ± 23%). CONCLUSIONS: Greater cardiac-parasympathetic function was associated with greater myocardial perfusion relative to left ventricular workload in healthy young adults. HRV and HRR are accessible and modifiable markers of cardiac-autonomic function that may be useful targets for young adults, particularly men, to reduce their future risk of ischemic heart disease. FUNDING: Supported by Georgia Southern University Faculty Research Committee Research Seed Funding Award.
Recommended Citation
John, Sandra, Meral Culver, Nathan K. McMillan, Brett L. Cross, Bryan Riemann, Gregory Grosicki, Andrew Flatt.
2024.
"Association Between Markers of Cardiacparasympathetic Function and Myocardial Oxygen Supply Demand Balance in Young Adults."
International Journal of Exercise Science: Conference Proceedings, 16 (3): West Kentucky University Press.
https://digitalcommons.georgiasouthern.edu/health-kinesiology-facpubs/327
Comments
Georgia Southern University faculty members, Bryan L. Riemann, Gregory J. Grosicki, and Andrew A. Flatt co-authored Association Between Markers of Cardiacparasympathetic Function and Myocardial Oxygen Supply Demand Balance in Young Adults.