Term of Award
Fall 2018
Degree Name
Master of Science in Applied Engineering (M.S.A.E.)
Document Type and Release Option
Thesis (restricted to Georgia Southern)
Copyright Statement / License for Reuse
This work is licensed under a Creative Commons Attribution 4.0 License.
Department
Department of Mechanical Engineering
Committee Chair
Dr. Mujibur Khan
Committee Member 1
Dr.Aniruddha Mitra
Committee Member 2
Dr.Marcel Ilie
Abstract
Drug loaded polymer polycaprolactone, polyethylene glycol particles were synthesized using Emulsion-Solvent-Evaporation (ESE) process, and particle characteristics studied using SEM (Scanning Electron Microscopy), EDS and drug release tests. Ternary phase diagrams were determined for oil-water emulsion (o-w) and water-oil emulsion (w-o) for the emulsion formation and destabilization. Hydrophilic drug 5-flourouracil (5-FU), cytarabine (CTB) and hydrophobic drug ibuprofen (IBP), paclitaxel (PXT) were investigated for drug encapsulation and release analysis for a period of 9-days at pH (=7,
OCLC Number
1096432176
Catalog Permalink
https://galileo-georgiasouthern.primo.exlibrisgroup.com/permalink/01GALI_GASOUTH/1fi10pa/alma9916218282402950
Recommended Citation
Kummari, Alfred R., "Emulsion Based Processing Of Drug Loaded Particles For Targeted Drug Delivery" (2018). Electronic Theses and Dissertations. 1869.
https://digitalcommons.georgiasouthern.edu/etd/1869
Research Data and Supplementary Material
No
