Chemistry: Faculty Publications (1990-2023)
Furanylidene Systems from a Tosylic Acid- Mediated, Tandem Desilylation-Cyclization Reaction of Silyl Ethers of Monoalkynylated Β -Keto Carbonyls
Document Type
Article
Publication Date
2011
Publication Title
Heterocyclic Communications
DOI
10.1515/HC.2011.044
ISSN
2191-0197
Abstract
Single isomers of the furanylidene system 8 were synthesized in four steps. The synthesis begins with the dianion of β-keto carbonyls and culminates in a mild, tandem desilylation-cyclization reaction using tosylic acid. Compounds synthesized in this study have the potential for further diversification at the alkyne, carbonyl and enol-ether moieties. Hence, the furanylidenes from this study are prospective building blocks for biologically active, furan-containing natural products and their analogs.
Recommended Citation
Oxford, John, Rayaj Ahamed, Morgan Hudson-Davis, Brandi Womack, Laura Gessner, Kristina Deveaux, Ebonni Fisher, Karelle Aiken.
2011.
"Furanylidene Systems from a Tosylic Acid- Mediated, Tandem Desilylation-Cyclization Reaction of Silyl Ethers of Monoalkynylated Β -Keto Carbonyls."
Heterocyclic Communications, 17 (5-6): 227-231: De Gruyter.
doi: 10.1515/HC.2011.044 source: https://www.degruyter.com/view/j/hc.2011.17.issue-5-6/hc.2011.044/hc.2011.044.xml
https://digitalcommons.georgiasouthern.edu/chem-facpubs/5
Copyright
This work is archived and distributed under the repository's Standard Copyright and Reuse License (opens in new tab). End users may copy, store, and distribute this work without restriction. For all other uses, permission must be obtained from the copyright owners or their authorized agents.
