Synthesis and Spectral Studies of (2-(furanyl)vinyl)-1-tetralone Chalcones

Authors

Sarah K. Zingales, Georgia Southern UniversityFollow
Andrew GoetzFollow
Jessica Futch
Kathryn Brown
Maya Z. Wallace
Morgan E. MooreFollow

Document Type

Article

Publication Date

1-1-2015

Publication Title

Heterocyclic Letters

ISSN

2230-9632

Abstract

Ten chalcones were synthesized by the crossed aldol condensation of substituted tetralones with furaldehydes. The products were purified by recrystallization in MeOH/H2O or by column chromatography in hexane/ethyl acetate and characterized by 1H NMR, 13C NMR, and HRMS. Evaluations of their biological activities are currently underway.

Recommended Citation

Zingales, Sarah K., Andrew Goetz, Jessica Futch, Kathryn Brown, Maya Z. Wallace, Morgan E. Moore. 2015. "Synthesis and Spectral Studies of (2-(furanyl)vinyl)-1-tetralone Chalcones." Heterocyclic Letters, 5 (4): 537-542. source: http://burrosk.wixsite.com/sarahkzingales/single-post/2015/11/05/Synthesis-and-Spectral-Studies-of-2-furanylvinyl-1-tetralone-Chalcones
https://digitalcommons.georgiasouthern.edu/chem-facpubs/114