Design and Synthesis of (2-(furanyl)vinyl)-1-tetralone Chalcones as Anticancer Agents

Document Type

Article

Publication Date

1-1-2016

Publication Title

Der Pharma Chemica

ISSN

0975-413X

Abstract

Ten chalcones (1a-e and 2a-e) were synthesized by the Claisen-Schmidt reaction. These compounds were submitted to PASS online for determination of likely biological activities and further QSAR analysis. These chalcones were predicted to have anticancer activity, specifically as inducers of apoptosis.

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