Visualization of Mercury(II) Accumulation in Vivo Using Bioluminescence Imaging with a Highly Selective Probe

Authors

• Bowen Ke, Sichuan University
• Hui Chen, Sichuan University
• Li Ma, Georgia Southern UniversityFollow
• Sarah Zingales, Armstrong State UniversityFollow
• Deying Gong, Sichuan University
• Die Hu, Sichuan University
• Lupei Du, Shandong University
• Minyong Li, Shandong UniversityFollow

Document Type

Article

Publication Date

1-1-2018

Publication Title

Organic and Biomolecular Chemistry

DOI

10.1039/c8ob00398j

Abstract

Mercury is a highly toxic environmental pollutant that negatively affects human health. Thus, an in vivo method for noninvasive imaging of mercury(II) and visualization of its accumulation within living systems would be advantageous. Herein, we describe a reaction-based bioluminescent probe for detection of mercury(II) in vitro and accumulation in vivo. The application of this probe would help to shed light on the intricate contributions of mercury(II) to various physiological and pathological processes.

Recommended Citation

Ke, Bowen, Hui Chen, Li Ma, Sarah Zingales, Deying Gong, Die Hu, Lupei Du, Minyong Li. 2018. "Visualization of Mercury(II) Accumulation in Vivo Using Bioluminescence Imaging with a Highly Selective Probe." Organic and Biomolecular Chemistry, 16: 2388-2392. doi: 10.1039/c8ob00398j source: https://pubs.rsc.org/en/content/articlelanding/2018/OB/C8OB00398J#!divAbstract
https://digitalcommons.georgiasouthern.edu/chem-facpubs/107

Copyright

This work is archived and distributed under the repository's Standard Copyright and Reuse License (opens in new tab). End users may copy, store, and distribute this work without restriction. For all other uses, permission must be obtained from the copyright owners or their authorized agents.