Biostatistics, Epidemiology & Environmental Health Sciences: Faculty Publications
Statistical Considerations for Clinical Trials During COVID-19: Natural History Controls for Survival Analysis (Part I)
Document Type
Article
Publication Date
4-8-2020
Publication Title
Abstract
To address this general difficulty, as well as various difficulties specific to impacts of COVID-19, we describe the approach of using natural history studies for comparative effectiveness analysis used in rare disease drug approval applications. This article is divided in three parts: substantial evidence standards, virtual matched control methodology, and inappropriateness of existing methods such as propensity score methods.
Recommended Citation
Liu, Qing, Karl E. Peace.
2020.
"Statistical Considerations for Clinical Trials During COVID-19: Natural History Controls for Survival Analysis (Part I)."
LinkedIn.
source: Linkedin.com
https://digitalcommons.georgiasouthern.edu/bee-facpubs/156
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