Histological Heterogeneity: A Case Study of Testicular Mixed Germ Cell Tumor
Faculty Mentor
Dr. Myka Bussey-Campbell
Location
Savannah Ballroom
Type of Research
Proposed
Session Format
Poster Presentation
College
Waters College of Health Professions
Department
Clinical Sciences
Abstract
Abstract
A Testicular Mixed Germ Cell Tumor (TGMCT) is the most common testicular neoplasm that consists of two or more types of malignant germ cell tumors. There is a peak occurrence in males between the ages of 25 and 34 years-old with a small palpable (and sometimes painless) lump being the most common symptom. An ultrasound examination was performed on a 32-year-old male who complained of a small palpable lump on the left testicle, during the exam both Duplex and Triplex imaging were utilized for obtaining diagnostic images. The patient indicated there was no trauma or family history of testicular cancer, and no lab work was completed for this patient. The ultrasound examination revealed the left testicle appeared heterogeneous with cystic components that had internal vascularity throughout the testis. An orchiectomy was performed, and the post-operative biopsy confirmed the diagnosis for testicular mixed germ cell tumor, but negative for malignancy. There are three treatment options for TGMCT which include a surgical option (orchiectomy), chemotherapy, and radiation therapy. There are no preventive measures, but undescended testis and family history are prominent risk factors.
Key words: testicular mixed germ cell tumor, neoplasm, malignant, ultrasound, testis
Program Description
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Start Date
4-21-2026 1:30 PM
End Date
4-21-2026 3:30 PM
Recommended Citation
Sexton, Hayley, "Histological Heterogeneity: A Case Study of Testicular Mixed Germ Cell Tumor" (2026). GS4 Student Scholars Symposium. 68.
https://digitalcommons.georgiasouthern.edu/research_symposium/2026A/2026A/68
Histological Heterogeneity: A Case Study of Testicular Mixed Germ Cell Tumor
Savannah Ballroom
Abstract
A Testicular Mixed Germ Cell Tumor (TGMCT) is the most common testicular neoplasm that consists of two or more types of malignant germ cell tumors. There is a peak occurrence in males between the ages of 25 and 34 years-old with a small palpable (and sometimes painless) lump being the most common symptom. An ultrasound examination was performed on a 32-year-old male who complained of a small palpable lump on the left testicle, during the exam both Duplex and Triplex imaging were utilized for obtaining diagnostic images. The patient indicated there was no trauma or family history of testicular cancer, and no lab work was completed for this patient. The ultrasound examination revealed the left testicle appeared heterogeneous with cystic components that had internal vascularity throughout the testis. An orchiectomy was performed, and the post-operative biopsy confirmed the diagnosis for testicular mixed germ cell tumor, but negative for malignancy. There are three treatment options for TGMCT which include a surgical option (orchiectomy), chemotherapy, and radiation therapy. There are no preventive measures, but undescended testis and family history are prominent risk factors.
Key words: testicular mixed germ cell tumor, neoplasm, malignant, ultrasound, testis
