Location

Nessmith-Lane Atrium

Session Format

Poster Presentation

Research Area Topic:

Public Health & Well Being - Epidemiologic Research

Co-Presenters, Co- Authors, Co-Researchers, Mentors, or Faculty Advisors

Titilope Ogunleke (Georgia Southern University)

Evans Afriyie-Gyawu (Georgia Southern University)

Jian Zhang (Georgia Southern University)

Abstract

Objective: To examine the relationship between serum levels of Vitamin A and precursors on Colorectal cancer mortality. Methods: A retrospective cohort study was conducted with 14,358 adults who participated in NHANES III. Data was collected via in home interviews and visits by participants to a mobile examination centre for blood sample collection. Characteristics such as family income, educational attainment, marital status, race and ethnicity, alcohol consumption, cigarette smoking, self reported health, type of resident, body size, cancer status at base line, vegetable consumption and fruit juice consumption were examined. Hazard ratio estimates for all-cause and cancer-related deaths among individuals with different serum Vitamin A levels were obtained form Cox Proportional Hazards Regression. Public Health Implications: Colorectal cancer is a serious public health issue. According to the CDC, In 2011, a total of 135,260 individuals were diagnosed with colorectal cancer and 51, 783 people died. Findings from this study can be utilized to conduct further research on the effects of Vitamin A and its precursors on colorectal cancer mortality and determine safe and effective dose for prevention. Additionally, findings from this study can be utilized to develop intervention strategies for colorectal cancer management, including educational interventions.

Keywords

Vitamin A, Cancer, Colorectal cancer, Prevention

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.

Presentation Type and Release Option

Presentation (Open Access)

Start Date

4-16-2016 10:45 AM

End Date

4-16-2016 12:00 PM

Included in

Epidemiology Commons

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Apr 16th, 10:45 AM Apr 16th, 12:00 PM

Effects of Serum Levels of Vitamin A and Precursors on Colorectal Cancer Mortlaity

Nessmith-Lane Atrium

Objective: To examine the relationship between serum levels of Vitamin A and precursors on Colorectal cancer mortality. Methods: A retrospective cohort study was conducted with 14,358 adults who participated in NHANES III. Data was collected via in home interviews and visits by participants to a mobile examination centre for blood sample collection. Characteristics such as family income, educational attainment, marital status, race and ethnicity, alcohol consumption, cigarette smoking, self reported health, type of resident, body size, cancer status at base line, vegetable consumption and fruit juice consumption were examined. Hazard ratio estimates for all-cause and cancer-related deaths among individuals with different serum Vitamin A levels were obtained form Cox Proportional Hazards Regression. Public Health Implications: Colorectal cancer is a serious public health issue. According to the CDC, In 2011, a total of 135,260 individuals were diagnosed with colorectal cancer and 51, 783 people died. Findings from this study can be utilized to conduct further research on the effects of Vitamin A and its precursors on colorectal cancer mortality and determine safe and effective dose for prevention. Additionally, findings from this study can be utilized to develop intervention strategies for colorectal cancer management, including educational interventions.