Location

Nessmith-Lane Atrium

Session Format

Poster Presentation

Research Area Topic:

Natural & Physical Sciences - Chemistry

Co-Presenters and Faculty Mentors or Advisors

Shainaz M. Landge (Georgia Southern University)

Abstract

Pyridazines are nitrogen-containing compounds that have been found to show a number of pharmaceutical applications. They exhibit antimicrobial, antifungal, and antibacterial properties to name a few. In particular: 3,4,6-triphenylpyridazine derivatives are known to possess anticancer properties. The purpose of this project is to synthesize tri-substituted pyridazine derivatives using microwave-assisted reactions, and to check its biological applications. Microwave synthesis will help shorten reaction times and produce high, efficient yields. Various catalysts, bases, reaction times, and temperatures will be explored to study the scope of the reactions.

DOI

10.20429/GS4.2016.022

Keywords

Microwave, Synthesis, Cancer, Pyridazines, Nitrogen-containing

Start Date

4-16-2016 10:45 AM

End Date

4-16-2016 12:00 PM

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.

Copyright

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Apr 16th, 10:45 AM Apr 16th, 12:00 PM

Microwave Assisted Synthesis of Tri-substituted Pyridazine Exploration

Nessmith-Lane Atrium

Pyridazines are nitrogen-containing compounds that have been found to show a number of pharmaceutical applications. They exhibit antimicrobial, antifungal, and antibacterial properties to name a few. In particular: 3,4,6-triphenylpyridazine derivatives are known to possess anticancer properties. The purpose of this project is to synthesize tri-substituted pyridazine derivatives using microwave-assisted reactions, and to check its biological applications. Microwave synthesis will help shorten reaction times and produce high, efficient yields. Various catalysts, bases, reaction times, and temperatures will be explored to study the scope of the reactions.