The impact of self-reported sleep duration and decline in kidney function of hypertensive patients in the United States
Abstract
Background: Researchers have identified sleep duration (SD) as a risk factor for health conditions like chronic kidney disease (CKD). However, limited research exists on the association between self-reported SD and kidney function (KF) decline, specifically among hypertensive patients in the United States (US). This study aims to investigate the impact of self-reported SD on KF decline within a large hypertensive population in the US.
Methods: Utilizing data from the National Health and Nutrition Examination Survey (NHANES 2017-2020), this study included participants with a mean age of 41.45±0.63. A decline in KF was defined as estimated glomerular filtration rates < 60 mL/min 1.73 m2, while SD was classified as10h. Logistic regression models were employed, adjusting for age, sex, ethnicity, physical activity, smoking, drinking, poverty-to-income ratio, education, blood pressure, obesity, total dysglycemia, and sleep quality.
Results: Self-reported SD significantly impacts the decline in KF (P10h. A reduction in the odds ratio (OR) was observed following covariate adjustments: risk of KF decline in participants with 8h vs 7h of sleep was 1.235 [95% CI: 0.537, 2.840] and [OR: 2.827 95% Cl: 1.220, 6.551] with[OR: 0.755, 95% CI: 0.104, 5.509] compared to females [OR: 5.904, 95% Cl: 1.222, 28.532].
Conclusion: Self-reported SD significantly influences the decline in KF. Optimal SD of 7h may be associated with a lower risk of KF decline, while sleeping(or 9h in females) may increase the risk. This risk factor should be considered in hypertension management to prevent CKD.
Keywords
Sleep duration, eGFR, chronic kidney disease, kidney function, hypertension
The impact of self-reported sleep duration and decline in kidney function of hypertensive patients in the United States
Background: Researchers have identified sleep duration (SD) as a risk factor for health conditions like chronic kidney disease (CKD). However, limited research exists on the association between self-reported SD and kidney function (KF) decline, specifically among hypertensive patients in the United States (US). This study aims to investigate the impact of self-reported SD on KF decline within a large hypertensive population in the US.
Methods: Utilizing data from the National Health and Nutrition Examination Survey (NHANES 2017-2020), this study included participants with a mean age of 41.45±0.63. A decline in KF was defined as estimated glomerular filtration rates < 60 mL/min 1.73 m2, while SD was classified as10h. Logistic regression models were employed, adjusting for age, sex, ethnicity, physical activity, smoking, drinking, poverty-to-income ratio, education, blood pressure, obesity, total dysglycemia, and sleep quality.
Results: Self-reported SD significantly impacts the decline in KF (P10h. A reduction in the odds ratio (OR) was observed following covariate adjustments: risk of KF decline in participants with 8h vs 7h of sleep was 1.235 [95% CI: 0.537, 2.840] and [OR: 2.827 95% Cl: 1.220, 6.551] with[OR: 0.755, 95% CI: 0.104, 5.509] compared to females [OR: 5.904, 95% Cl: 1.222, 28.532].
Conclusion: Self-reported SD significantly influences the decline in KF. Optimal SD of 7h may be associated with a lower risk of KF decline, while sleeping(or 9h in females) may increase the risk. This risk factor should be considered in hypertension management to prevent CKD.
