Term of Award
Master of Arts
Document Type and Release Option
Thesis (restricted to Georgia Southern)
Department of Psychology
Paul R. Kleinginna, Jr.
Committee Member 1
J. Peter Kincaid
Committee Member 2
In the past three decades, a number of researchers have found a relationship between ethanol (ETOH) consumption and diet. The present study was concerned with the effect of megadoses of pyridoxine hydrochloride, Vitamin B6, on ETOH consumption in 18 male rats, approximately 120 days old at the initiation of the study. The rats were allowed to become familiar with the chemical and physiological properties of ethanol during four ETOH selection series, termed Acclimation Condition. Following Acclimation, the rats were divided into two equivalent groups, Vitamin Group and Control Group, based on total ETOH consumed during the four selection series. Throughout the two final ethanol selection series (Experimental Condition), the Vitamin Group received daily 200 mg/kg intraperitoneal injections of pyridoxine hydrochloride. The Control Group received a volumetrically equivalent injection of bacteriostatic water. A split-plot factorial analysis did not reveal a between groups difference in the ethanol intake due to vitamin injections.
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Hoover, Sandra Gail, "The Effect of Megadoses of Pyridoxine Hydrochloride on the Volitional Consumption of Ethanol in Acclimated Rats" (1977). Legacy ETDs. 902.