Term of Award

Summer 1987

Degree Name

Master of Science

Document Type and Release Option

Thesis (restricted to Georgia Southern)

Committee Chair

Sara Neville Bennett

Committee Member 1

Wayne A. Krissinger

Committee Member 2

Donald J. Drapalik


Six vinclozolin-resistant mutants of N. crassa obtained following ultraviolet irradiation and selection on vinclozolin media, showed 1:1 segregation of the vinclozolin-resistant trait. In addition to being vinclozolin resistant, the six mutants had altered, non-wild-type morphology and were osmotic sensitive, with the different mutants exhibiting varying degrees of sensitivity. Genetic analysis indicated linkage of the three traits. Reappearance of osmotic sensitivity/altered morphology in crosses of phenotypically recombinant F3 progeny supported the presence of modifier(s). Rates of growth on vinclozolin media placed the six mutants into three groups. In most cases the rates were comparable to rates of growth on W-M media. Preliminary genetic analysis indicated linkage of three mutants to linkage groups I or II. Another mutant was linked to mating type with an 8% recombination.


To obtain a full copy of this work, please visit the campus of Georgia Southern University or request a copy via your institution's Interlibrary Loan (ILL) department. Authors and copyright holders, learn how you can make your work openly accessible online.

Files over 10MB may be slow to open. For best results, right-click and select "Save as..."