Term of Award

Fall 2007

Degree Name

Master of Science in Biology (M.S.)

Document Type and Release Option

Thesis (open access)

Department

Department of Biology

Committee Chair

James B. Claiborne

Committee Member 1

Chris Cutler

Committee Member 2

Daniel Gleason

Abstract

Acid-base regulation is a vital mechanism in homeostasis. Fish must maintain optimal physiological acid-base parameters during changes in an aquatic habitat. Environmental factors such as changes in salinity affect fish ability to maintain optimal blood plasma ion concentrations. Ion regulation influences the fish ability to maintain optimal acid-base balance. The Na+/H+ Exchanger-3 (NHE-3) has been shown to be the primary membrane ion transporter responsible for acid-base balance in the mammalian kidney. The objective of this study is to characterize NHE-3 in the gills of longhorn sculpin (Myoxocephalus octodecimspinosus).

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