Title

Effect of Cortisol on Aquaporin Expression in the Oesophagus of the European Eel, Anguilla anguilla

Document Type

Article

Publication Date

4-2005

Publication Title

Annals of the New York Academy of Sciences

DOI

10.1196/annals.1327.072

ISSN

1749-6632

Abstract

Long‐term cortisol infusion into freshwater (FW)‐adapted eels induced a significant increase in aquaporin‐1 (AQP1) mRNA expression within the esophageal epithelium of migratory “silver” eels, but not in nonmigratory, immature “yellow” eels. Cortisol treatment had no significant effect on the mRNA abundance of a second aquaporin‐1 isoform, termed AQP1dup, which exhibited a highly variable expression profile among individual members of all fish groups. These results suggest that cortisol, at plasma concentrations similar to that found during FW/seawater (SW) acclimation, induces upregulation in AQP1 expression and thus increases esophageal water permeability during the migration of eels to the SW environment.

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