The Fibroadenoma Imposter: Diagnostic Challenges and Management of Well-Circumscribed Nodular Pseudoangiomatous Stromal Hyperplasia (PASH)

Faculty Mentor

Dr. Myka Bussey-Campbell

Location

Savannah Ballroom

Type of Research

Proposed

Session Format

Poster Presentation

College

Waters College of Health Professions

Department

Clinical Sciences

Abstract

Abstract

This case study demonstrates a 48-year-old, white, premenopausal female with a palpable, painless lump in her right breast who came in for a regularly scheduled mammogram. The mammogram came back abnormal, and the patient was referred to ultrasound. The ultrasound visualized a small, round, well-circumscribed hypoechoic mass in the middle-upper quadrant of the breast, correlating to the location of palpation. The mass was suspected to be a fibroadenoma, however the patient was scheduled for a biopsy in order to confirm this. The biopsy results instead indicated pseudoangiomatous stromal hyperplasia (PASH). PASH is a benign proliferative lesion of stromal tissue found within the breast, typically in women who are premenopausal. It is believed to be influenced by hormones and is often asymptomatic. It has been known to have a significant recurrence rate when surgically removed. This case study demonstrates that not all well-circumscribed hypoechoic masses are fibroepithelial lesions and aims to address why differentiating between PASH and a fibroadenoma can be important for treatment in some cases.

Keywords: pseudoangiomatous stromal hyperplasia, benign breast lesions, fibroadenoma, breast ultrasound

Program Description

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Start Date

4-21-2026 1:30 PM

End Date

4-21-2026 3:30 PM

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Apr 21st, 1:30 PM Apr 21st, 3:30 PM

The Fibroadenoma Imposter: Diagnostic Challenges and Management of Well-Circumscribed Nodular Pseudoangiomatous Stromal Hyperplasia (PASH)

Savannah Ballroom

Abstract

This case study demonstrates a 48-year-old, white, premenopausal female with a palpable, painless lump in her right breast who came in for a regularly scheduled mammogram. The mammogram came back abnormal, and the patient was referred to ultrasound. The ultrasound visualized a small, round, well-circumscribed hypoechoic mass in the middle-upper quadrant of the breast, correlating to the location of palpation. The mass was suspected to be a fibroadenoma, however the patient was scheduled for a biopsy in order to confirm this. The biopsy results instead indicated pseudoangiomatous stromal hyperplasia (PASH). PASH is a benign proliferative lesion of stromal tissue found within the breast, typically in women who are premenopausal. It is believed to be influenced by hormones and is often asymptomatic. It has been known to have a significant recurrence rate when surgically removed. This case study demonstrates that not all well-circumscribed hypoechoic masses are fibroepithelial lesions and aims to address why differentiating between PASH and a fibroadenoma can be important for treatment in some cases.

Keywords: pseudoangiomatous stromal hyperplasia, benign breast lesions, fibroadenoma, breast ultrasound