Regulation of Transcription by Synthesizing Peptide Mimics of Transcription Factor NF-KB

Location

Statesboro Campus, Russell Union, Room 2048, Session 1

Document Type and Release Option

Thesis Presentation (Open Access)

Faculty Mentor

Dr. Amanda White

Faculty Mentor Email

alstewart@georgiasouthern.edu

Presentation Year

2022

Start Date

22-4-2022 11:00 AM

End Date

22-4-2022 12:00 PM

Description

The NF-KB protein regulates genes important for apoptosis, immune response, and cell growth and differentiation. The binding capacities and the structure of three NF-KB mimics will be studied using circular dichroism and isothermal titration calorimetry or fluorescence spectroscopy aiming to eventually prevent overexpression of proteins by the NF-KB transcription factor.

Academic Unit

College of Science and Mathematics

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Apr 22nd, 11:00 AM Apr 22nd, 12:00 PM

Regulation of Transcription by Synthesizing Peptide Mimics of Transcription Factor NF-KB

Statesboro Campus, Russell Union, Room 2048, Session 1

The NF-KB protein regulates genes important for apoptosis, immune response, and cell growth and differentiation. The binding capacities and the structure of three NF-KB mimics will be studied using circular dichroism and isothermal titration calorimetry or fluorescence spectroscopy aiming to eventually prevent overexpression of proteins by the NF-KB transcription factor.