Cyanide derivative of truxillic acid
Primary Faculty Mentor’s Name
Koushik Banerjee
Proposal Track
Student
Session Format
Poster
Abstract
The photodimerization of trans-cinnamic acid creates truxillic acid. This is a [2+2] solid state photocycloaddition reaction. Some have worked with different cinnamic acid polymers to create light induced shape memory polymers. Others have worked with the truxillic acid to create a derivative can successfully inhibit fatty acid binding proteins (FABPs). This is very important for anti-inflammatory drugs.
We started with 4-cyanobenzaldehyde and synthesized 4-cyano trans-cinnamic acid using a green method. The yield with a small sample was 81%. Upon scale up, the product had a 74% yield. The photo-product had an 87% conversion based on 1H-NMR studies.
Keywords
photodimerization cyanide derivative truxillic acid
Location
Concourse and Atrium
Presentation Year
2015
Start Date
11-7-2015 2:10 PM
End Date
11-7-2015 3:20 PM
Publication Type and Release Option
Presentation (Open Access)
Recommended Citation
Green, Karlton P., "Cyanide derivative of truxillic acid" (2015). Georgia Undergraduate Research Conference (2014-2015). 43.
https://digitalcommons.georgiasouthern.edu/gurc/2015/2015/43
Cyanide derivative of truxillic acid
Concourse and Atrium
The photodimerization of trans-cinnamic acid creates truxillic acid. This is a [2+2] solid state photocycloaddition reaction. Some have worked with different cinnamic acid polymers to create light induced shape memory polymers. Others have worked with the truxillic acid to create a derivative can successfully inhibit fatty acid binding proteins (FABPs). This is very important for anti-inflammatory drugs.
We started with 4-cyanobenzaldehyde and synthesized 4-cyano trans-cinnamic acid using a green method. The yield with a small sample was 81%. Upon scale up, the product had a 74% yield. The photo-product had an 87% conversion based on 1H-NMR studies.
