Isolation and Characterization of LMWCr from Chicken Liver
The Protein Journal
Chromodulin (also known as low-molecular-weight chromium-binding substance, LMWCr) is a chromium-binding oligopeptide proposed to play a role in insulin signaling and chromium transport in mammals. This laboratory has isolated and purified this material from a non-mammalian source, an avian. Spectroscopic and physical characterization of the isolated material suggests the material is an oligopeptide with a multinuclear chromium assembly bridged via asparatate and glutamate residues very similar to its mammalian counterparts. The isolated material also possesses a biological activity similar to other LMWCr isolates.
Davis McGibony, C. Michele, Margarita Viera.
"Isolation and Characterization of LMWCr from Chicken Liver."
The Protein Journal, 27 (6): 371-375.